Research Summary

Manual Lymphatic Drainage for Breast Cancer Lymphoedema: What 17 Trials Found

Full Study Details

Manual Lymphatic Drainage for Lymphedema in Patients After Breast Cancer Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Liang M, and colleagues
Published in: Medicine (Baltimore), 2020; 99(49): e23192
DOL: 10.1097/MD.0000000000023192 (open access)
Study design: Systematic review and meta-analysis of 17 randomised trials (1911 patients)

What the study looked at

Swelling of the arm, known as lymphoedema, is a common and distressing consequence of breast cancer surgery, particularly when lymph nodes are removed. Manual lymphatic drainage (MLD) is a gentle, hands-on technique widely used to help manage it, and this large review set out to test how well it actually works.
The authors pooled 17 randomised controlled trials involving 1911 patients, examining whether MLD helps prevent lymphoedema and whether it reduces swelling and improves symptoms in people who already have it.

Why this matters to practitioners

Breast cancer-related lymphoedema is one of the most common reasons people are referred for lymphatic drainage. A large review helps show where MLD genuinely helps and where expectations should be measured.

What the treatment involved

Manual Lymphatic Drainage

Light, rhythmic, skin-stretching strokes that follow the lymphatic pathways to encourage excess fluid to move away from the swollen arm.

As Part of a Plan

MLD is typically used alongside compression, exercise and skin care, together known as Complete Decongestive Therapy, rather than on its own.

What the results showed

The evidence was encouraging for swelling, and more mixed for other outcomes.

May Help Prevent Swelling

Some evidence suggested MLD may reduce the risk of developing lymphoedema after breast cancer surgery, though this remains debated.

Reduces Swelling Volume

Adding MLD to standard care was associated with greater reductions in arm swelling volume in several trials.

Symptoms Less Certain

Benefits for subjective symptoms such as heaviness, and for arm function, were less consistent across studies.

Safe and Gentle

MLD is low-risk and well tolerated, making it a reasonable component of lymphoedema care.

Key finding in plain terms

Manual lymphatic drainage, used alongside compression and exercise, was associated with reduced arm swelling in breast cancer-related lymphoedema, with a possible role in prevention, though its effect on symptoms and function is less certain.

What this means for lymphatic drainage and post-surgical care

This supports MLD as a genuine, evidence-informed part of managing breast cancer-related swelling, best delivered within a broader plan that includes compression, movement and skin care, and in coordination with the person’s medical team.
It also encourages honest expectations. MLD can help move fluid and support comfort, but it is one part of a package, not a stand-alone cure, and results vary from person to person.

Clinical relevance by discipline

Manual Lymphatic Drainage

Directly supports MLD as a core technique for breast cancer-related swelling, delivered within Complete Decongestive Therapy.

Remedial Massage

Reinforces gentle, appropriate soft-tissue and scar work as part of recovery, always within scope and with medical clearance.

Myotherapy

Of interest for supporting comfort and movement around the shoulder and arm alongside lymphatic care.

Sports Treatment

Limited direct relevance; included for completeness rather than treatment application.

Limitations to be aware of

The included trials varied in quality, in how MLD was delivered, and in how swelling was measured, which lowers certainty. Notably, some reviews, including a Cochrane review, have not found a clear added benefit of MLD within Complete Decongestive Therapy, so the evidence is genuinely mixed.
The honest reading is that MLD may help swelling volume and is safe, but it should be framed as part of a package. Please confirm the citation details and author list against the source before publishing.

Summary

Pooling 17 trials with 1911 patients, this review found MLD was associated with reduced arm swelling in breast cancer-related lymphoedema, with a possible preventive role, though effects on symptoms and function were less certain and some reviews find limited added benefit.
For lymphatic drainage practitioners, it supports MLD as a valued part of a broader plan, delivered with medical coordination and realistic expectations.

Manual lymphatic drainage is available at MyoFitness.

North Melbourne, Yarraville, and Surrey Hills. No referral required. Book online or call 03 9028 4087.

Full Research Paper

Manual Lymphatic Drainage for Lymphedema in Patients After Breast Cancer Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Liang M, and colleagues. Medicine (Baltimore), 2020; 99(49): e23192.